Patient-specific biomechanical simulation of transcatheter aortic valve replacement.
Cristoforetti A., Masé M., Bonmassari R., Nollo G., Ravelli F.
Transcatheter aortic valve (TAV) replacement holds promise for the treatment of aortic valve stenosis in patients who have a higher risk for open heart surgery. Procedure planning, accurate device positioning, and complication minimization may benefit from patient-specific biomechanical simulations. We developed a damped mass-spring simulation model based on patient-specific aortic root anatomy derived from pre-operative CT-scan. Preliminary results in patients undergoing TAV replacement procedure showed the ability of the model to reproduce the aortic root mechanical response to TAV deployment, accounting for the specific geometry, tissue parameters, and calcification location.