Asymmetric Mach-Zehnder Interferometer based biosensing system for Aflatoxin M1 detection in milk.
Chalyan T., Potrich C., Falke F., Schreuder E., Heideman R.G., Pederzolli C., Adami A., Pavesi L.
In this work, we present a biosensor system based on a label-free approach for Aflatoxin M1 (AFM1) detection, known as a carcinogenic toxin present in milk. Milk is a complex matrix, including multiple phases and several chemical species. Therefore, before sending to the sensor, milk needs to be treated and purified. The proposed system consists of three modules: a milk sample preparation module, a concentrator module and a photonic sensor which is based on asymmetric Mach-Zahnder Interferometers that are optimized for 850 nm wavelength. The described system detects AFM1 at the 50 ng/L level, which is in agreement with EU regulations.